The focus of the lab is to understand how adverse experiences encountered early in life alter the trajectory of neural development and the genetic mechanisms supporting those changes. We seek to understand this question through an evolutionary lens, and attempt to understand how changes in the timing of regional brain development support the proximate goals of survival and reproduction, with implications for expressions of pathological behavior in the instance of a mismatch between the rearing context and the context an animal subsequently finds itself in. To this end, the lab focuses on the development of multiple brain centers, including the social behavioral network, limbic, paralimbic, and cortical brain areas and behaviors associated with the development of each.

OUR APPROACH

Projects in the Bath lab use mouse models to test the impact of Early Life Stress on the trajectory of neuroanatomical and behavioral development. We use a variety of techniques including behavioral assays, realtime qPCR, histology, genetically engineered mouse lines, ELISA, optogenetics, stem cell cultures, seahorse metabolic assays, and Western blot analysis.

Neurobiology of Stress 2022- Poster Night

Travel Awardees- Neurobiology of Stress (Camila)

Lab Bowling and Times Square Holiday Party

lab 2017

Find out about our lab our methods, and the results of our work.

Lab Picnic